Risk factor is defined as any thing due to which chances of getting any diseases spiral up and in connection with breast cancer those women who are in possession of more said risk factors likely than others to get breast cancer more frequently and commonly Exact diagnose of any disease is the way which leads toward accurate and best treatment.
specialist hardly diagnose why one woman develops breast cancer and other does not,majority of the women who have developed breast cancer will never be aware of the exact cause of cancer.according to the research it is proved that breast cancer is always caused by damage to important part of cell known as DNA.It means that in women a risk element is some thing that may spiral up the probability of developing cancer ,and among these factors some factors like drinking of alcohol can be controlled but most risk element like ,having family history of breast cancer is impossible to eliminate.Commonly breast cancer begins and develops initially in the inner lining of milk ducts or it may be in the lobules.It is a particular type of malignant tumor which can spread gradually to the other parts of body and causing cancer to these parts of body as well.If the breast cancer commences in lobules it is called lobular carcinoma whereas if this cancer begins from the ducts then it is known as ''ductal carcinoma ''Maximum cases of the breast cancer are related to women.It is fact that it is the most common invasive in women across the globe.According to a survey it has been reported that nearly 16% women developed cancer among which approximately 22.9% is invasive cancer.The death ratio is 18.2% including male and female both.due to aforesaid cancer.
It is very surprising and incredible ratio of breast cancer in developed countries and developing countries.Its ratio in advance and developed countries like USA,UK,France,Germany Canada etc are much higher than developing and poor countries.There a lot of reasons behind this cancer depending upon the various factors.This cancer more frequently and more commonly develops in elder women.More over the lives of women in advance countries are longer than backward or developing countries.In addition to this an other vital factor behind this disease is different life style and eating habits of females in developed and developing countries.National cancer institute of USA recorded alarming figure of male and female on yearly basis.According to the latest report of N.C.I. in America 232,340 female and 2,240 male and 39,620 death cases were reported which is a matter of great concern and alarming.
Patient can better utter symptoms of disease,who is suffering from.Most common and very frequent symptom is thickened tissues in female breast just like lump but it does not mean that every lump would be cancer.Doctors can better decide about the nature of this lump or bread cancer.Let's have a birds eye view of some common and major symptoms of breast disease as appended below for your information and further necessary remedial actions.
(1) Lump-lose thickness in breast
(2) The visibility of peel,scale,or flake on breast particularly on nipple skin
(2) The visibility of peel,scale,or flake on breast particularly on nipple skin
(3)Observation of red skin like orange on breast
(4) Abnormality in size and shape of breast
(5) Appearance of swelling in armpits
(6) The shape of nipple becomes sunken or inverted
(7) Feeling of pain in armpit or breast
(8) Discharge of blood from nipples
(9) appearance pf rash on nipples
(10) Specific area full of thickened tissues in breast.
New drugs for breast cancers
New type of breast cancer drug can play important role in the treatment of many more women developing cancer.As regard biological therapies at present it is only clinical trials and no more than this.According to the expert opinion this new drug only one can benefit five patients. According to the scientist only in the UK near about 10,000 women might benefit from new drugs regarding breast cancer.Breast cancer due to BRCA, which is inherited genetic errors, can be treated by biological therapies.Holly wood queen of beauty Angelina Jolie is also carrying same cancer.According to the suggestion given by the experts from Wellcome Trust Sanger Institute,they told that these drugs may work in those women who are free from these risky genes so for.It means this drug is sufficient and effective in one in five breast cancer.According to the reliable survey and estimate out of 20% patients,there are almost 5% patients who are in possession of BRCA genes.The treatment of biological therapy is already used on the NHS for the treatment of particular type of advanced ovarian cancer,and it is also known as PARP inhibitor known as olaprib. Although same new drug not yet recommended and approved for the treatment of breast cancer but despite this,many women are using same drug merely on the basis of clanical trials.In the process of this drug preparation nearly 560 different patient were brought under experience and research was carried out properly at the genetic make up of this breast cancer.Ultimately they met with very useful and significant conclusions regarding this disease.In this research they met with ''mutational signatures''which were quite similar to the aforesaid faulty BRCA.They reached at the conclusion that due to close resemblance these cancer might be treatable with the help of biological therapies.They approved that first of all patient should be confirmed on clinical trials.According to the statement of Dr Helen Davis ''there was also potential to cure cancer of other category with the help of these new drugs''.That is why biological therapies have already shown very positive result even for the treatment of prostate cancer too.The functions of these cells are entirely changed and this change help to control the body which is very helpful measure to control the cancer.
BRCA is the most dangerous mutational genes because there is maximum risk of developing breast cancer in those women who are in possession of gene mutation particularly BRCA. But this does not mean that any women carrying gene mutation having breast cancer it is not obligatory,however the probability of acquiring breast cancer spiral up in these women.IT means that there is only assumption or probability to get breast cancer if any woman found with BRCA or any other gene mutation.For safety precaution famous Holly wood actor Angelina Jolie got surgery from lower part of her breast to save remaining part of body from the spreading breast cancer to other part ob body as well as breast because it was entirely life time risk. In the same Vicki Gilbrit of 54 developed cancer because she already had high risk gene that is why she developed breast cancer.She told that she by all means wanted to go under various test regarding cancer because she knew that already her family had a lot of cancer patients ,now she wanted to verify and clarify her case in the light of necessary tests.Ultimately i was diagnosed with breast cancer after the result report of aforesaid test.More over she added that i was sure genes that i inherited could be cause of breast cancer. For nearly seven years she has been free from this disease but even now a days for safety precaution she is getting her regular check and necessary test due to her high genetic risk.All female can reduce the life time risk of breast cancer by
(a) Regular exercise
(b) Good diet
(c) Healthy weight
(d) No smoking
(e) Reducing alcohol
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